Diastop

Therapeutic Class

Antidiarrheals

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Oral Suspension (NRN: 04-1393): Kaolin light BP 200 mg per mL.

Pack size: 100 mL.

Pharmacology

Diastop suspension is an orally effective anti-diarrhoeal preparation. It contains Kaolin Light as the active ingredient, hence, it is an adsorbent which is effective in the symptomatic treatment and control of diarrhoea.

Indications

Diastop Suspension is the pharmaceutical preparation which work by absorbing potential toxins i.e., toxic agents from bacteria or germs that may cause diarrhoea. Hence, Diastop Suspension is used in arresting mild to moderate diarrhoea of any aetiology in patients.

Contra-indications

Contraindicated in patients who are sensitive to kaolin preparations and other components of the mixture.

Precautions/Warnings

This Suspension contains Kaolin Light BP. Do not take any other medications containing Kaolin Light at the same time.

The fluid loss caused by diarrhoea may result in a severe dehydration. It is therefore very important that a sufficient amount of liquid be given to replace the fluid loss from the body.

Concurrent administration of Diastop Suspension with other drugs e.g. Lincomycin, Tetracycline, may reduce the absorption of the later drugs.

Interactions

Kaolin has been noted to interact with the quinolone antibiotics, Lincomycin, Tetracycline. The effect is a reduced absorption of these medicaments thereby resulting in lower plasma concentrations.

Adverse Effects

When taken in recommended doses, Diastop Suspension is usually free from side effects, since Kaolin Light is not absorbed from the Gastro-intestinal tract. Excessive doses may lead to constipation.

Dosage & Administration

Important Information: Treatment with Diastop Suspension should be accompanied by plenty of fluid intake and electrolyte replacement e.g., Oral rehydration fluids, salt and sugar solution, and soft drinks.

Food such as vegetable, fruit pepper, fried foods, candy, coffee and alcoholic beverages should be avoided during treatment of diarrhoea as these tend to aggravate the condition.

Signs of Danger in Diarrhoea: If too much has been lost by the body due to diarrhoea, a serious condition may develop. See a doctor immediately if any of the following signs or symptoms occur:

• Decreased urination
• Dizziness
• Light headedness
• Dryness of mouth
• Increased thirst
• Wrinkles on the skin.

Storage/Handling Recommendations

Store Diastop in a cool dry place and out of the reach of children.